Nicotine Salt Solutions

Nicotine Salts - Combo Graphic

“Signature,” “Hit,” and “Smooth” Nicotine Salt formulations are designed around harnessing the differing properties of nicotine inhalation character. Each of these three formulae are a differing blend of multiple cationic acids known to bind electro-negative nicotine on the tobacco leaf, and others that we have unique IP in-development at the laboratory!

Numerous cationic acids exist on the tobacco leaf; we know this since the pH of tobacco smoke is closer to 5 on the pH scale (1-14) than that of the basic nicotine, which is closer to 8. These acids possess positive charges, AKA free hydrogens, with exhibit attraction to nicotine’s basic nitrogen centers. This is nature’s beautiful way of stabilizing the nicotine molecule for prolonged activity and defense against oxidative degradation. The binding of a cationic salt at nicotine’s electronegative nitrogen center(s), inhibits the oxidative damage it would suffer in comparison to a non-salt formulation!

X-Ray Crystallography and other data from literature was aggregated in-lieu of traditional GC/MS or LC/MS reports due to the weaker binding forces that hold these cationic-anionic pairs together. Basically, they have to be frozen down to cryogenic temperatures to lock bonds in-place and then analyzed in-situ. This reveals the pairs of nicotine and acid bound together that would normally be separated when solvated into solution! We are able to bind these pairs in-situ at the Nude Nicotine laboratory pre-dilution to achieve this effect.

Nicotine Salts are formulated at 100mg/mL concentration and diluted in PG or VG and ready for use immediately. The use of the cationic salts may accelerate the color change of the nicotine salt solution, but is by no means indicative of oxidation therein. The binding of the two molecules results in a sharing of electrons from the cationic salt with the anionic nicotine, resulting in color!!!

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